Letrozole: Description of the Drug

Letrozole is a medication primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. It belongs to a class of drugs known as aromatase inhibitors, which work by decreasing estrogen levels in the body. This reduction is crucial because many breast cancers rely on estrogen to grow.

Mechanism of Action

The primary action of letrozole involves inhibiting the aromatase enzyme, responsible for converting androgens into estrogens. By blocking this enzyme, letrozole effectively lowers circulating estrogen levels, thus slowing or stopping the growth of estrogen-sensitive tumors.

Indications

Letrozole is indicated for:

Dosage and Administration

The usual dose of letrozole is 2.5 mg taken orally once daily. Treatment duration can vary based on individual https://letrozoleonline.com/products/letrozol-denk-2-5mg-filmtabletten/ patient factors and response to therapy. It is essential for patients to follow their healthcare provider’s instructions regarding dosage and duration.

Side Effects

letrozole can be effective, it may also lead to several side effects. Commonly reported side effects include:

Patients should inform their healthcare provider of any severe or persistent side effects, as there may be alternatives or supportive treatments available.

Contraindications and Precautions

Letrozole is contraindicated in:

Before starting treatment, it is important for patients to discuss their complete medical history with their healthcare provider, including any history of osteoporosis or liver disease, as these conditions may influence treatment decisions.

Conclusion

Letrozole plays a significant role in the management of hormone receptor-positive breast cancer among postmenopausal women. Its ability to lower estrogen levels makes it an effective option for reducing tumor growth and preventing recurrence. As with all medications, understanding its use, potential side effects, and necessary precautions is vital for maximizing therapeutic outcomes.

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